400 Level Courses

411 Computational Chemistry
A survey of modern computational chemistry methods, focusing mainly onDensity functional theory. This course is addressed to honors studentsmainly. Areas of interest include accurate predictions of geometries,energetics, and reaction mechanisms as well as IR, Raman, UV and NMRspectra.
Prerequisite: CHEM 330, 341 (completed or concurrent). Three credits and research project.
-March 2006-

421 Physical Organic Chemistry and Organic Spectroscopy
A survey of theoretical models and experimental tools to correlated data related to the structure, property, and reactivity of organic compounds. Topics include qualitative models (resonance, hybridization, VSEPR, qualitative molecular orbital theory), quantitative computational chemistry methods (Hartree-Fock, semi-empirical and density functional theory methods), and spectroscopic methods (IR and NMR). Extensive use is made of theoretical and spectroscopic studies in assignments, computational and experimental labs.
Prerequisites: CHEM 220, CHEM 232, PHYS 120. Three credits and lab.
- February 2007 -

422 Advanced Organic Chemistry: Structure and Mechanism (Outline)
Building on the structures and energetics of organic reactive intermediates, this course will examine their role in reaction mechanisms. Several important classes of reactions will be analyzed in detail with respect to stereoelectronic effects. This course will also examine some of the methodology used to determine organic reaction mechanisms. The synergy between experimental and computational results will be discussed.
Prerequisite: CHEM 421. Three credits and lab.
- February 2007 -

432 Electrochemical Methods
This course investigates modern electrochemical techniques, including potential step and potential sweep methods, pulse voltammetry, controlled-current experiments, hydrodynamic voltammetry, and AC impedance. Particular attention will be given to processes that occur at the electrode-solution interface in the use of these techniques (mass transport, charge transport kinetics, current-time and current-potential profiles). Topics of current interest, such as fuel cells, chemically modified electrodes, corrosion, ion-selective electrodes, ultramicroelectrodes, and catalysis will also be studied.
Prerequisite: CHEM232, 360 (concurrent). Three credits and lab.
-March 2006 -

434 Colloids and Polymers 
The properties of colloids, surfaces, interfaces, and polymers will be discussed from a theoretical and an applied perspective. The course will begin with a qualitative description of the colloidal state, including the various types of colloids and their preparation and properties. Topics will include: experimental techniques used to determine colloidal properties; interfacial phenomena, including the measurement of surface and interfacial tension, the wetting of surfaces, and contact angles; and the properties of surface active agents, charged interfaces, and the stabilization of colloidal systems.
Prerequisites: CHEM 231, 232. Three credits and laboratory. Offered in alternate years.
- June 2004 -

435 Introduction to Polymer Chemistry (Outline)
This course introduces the basic principles and techniques employed in polymer chemistry. The following topics are emphasized: polymerization reactions and mechanisms; kinetics of polymerization; molecular mass methods; molecular sizes and shapes; polymer morphology; thermal, mechanical and rheological properties; and the thermodynamics of polymer solutions.
Prerequisites: CHEM 220, 231, 232. Three credits, no laboratory. Offered in alternate years.
- June 2004 -

442 Bio-Inorganic Chemistry 
A survey of metal ions in biological systems. Topics include: ion pumps, oxygen carriers such as hemoglobin, metalloenzymes, nitrogen fixation, photosynthesis, biologically important trace metals, biomimetic systems and inorganic drugs. Discussion of various physical techniques used in bio-inorganic chemistry will also be included.
Prerequisites: CHEM 341; CHEM 342 completed or concurrent. Three credits and laboratory. Offered in alternate years.
- June 2004 -

443 Inorganic Materials (Outline)
Discussion of current areas of interest in inorganic materials research. Topics include: superconductors, magnetic and electronic materials, nonlinear optics, polymeric coordination complexes, biogenic materials, intercalation compounds and liquid crystals.
Prerequisites: CHEM 341; CHEM 342 completed or concurrent. Three credits and laboratory. Offered in alternate years.
- June 2004 -

445 Introduction to Photochemistry and Applications in Sustainable Catalysis (Outline)
An introduction to photochemistry with a focus on current catalytica applications.  The course will focus on the fundamental concepts of photochemistry and light induced chemistry of common organic fucntional groups.  Modern applications of photochemistry incatalysis involving transiton methals, semiconductors, supramolecular materials, and nanomaterials will also be discussed.
Prerequisites: CHEM 220 (221,222) CHEM 225.  Three credits.
- June 2015-

 451 Bio-Organic Chemistry I
A discussion of isomerism and proisomerism is followed by an analysis of the reactions observed in the biosynthesis of amino acids. The dominant theme is a development of reaction mechanism possibilities in biological reactions.
Prerequisite: CHEM 220. Three credits.
- May 2008 -

452 Bio-Organic Chemistry II
The dominant theme, continuing from CHEM 451, is the development of reaction mechanism possibilities in biological reactions. An analysis of the reactions observed in the biosynthesis of terpenoids is followed by an examination of the mechanisms of action of a number of enzymes based on the protein structure, active site geometry and amino acid residues therein.
Prerequisite: CHEM 451. Three credits.
- May 2008 -

455 - Medicinal Chemistry 
Topics include the drug development process, receptors, drug interaction, pharmacodynamics, pharmacokinetics and quantitative structure activity relationships. Chemical properties and mode of action of some of the following classes of drugs will be discussed: antibacterial drugs, drugs that work on the central nervous system, anticancer drugs, antiviral drugs, and analgesics. Case studies of current drugs going through the approval processes will be included.Prerequisites: CHEM 220, 255. Three credits and laboratory. Offered in 2005/06 and in alternate years
-July 2005-

461 Topics in Instrumentation and Analysis 
This course typically starts with a brief introduction to electronics, signals, noise and data manipulation. This is followed by a survey of molecules with bioanalytic applications (enzymes, immunoglobulins, avidin/biotin, cyclodextrins), and a discussion of selected bioanalytic methods and their applications in sensors. A variety of instrumentation is used in the lab, with some attention paid to assembly of equipment, maintenance and repair.
Pre- or co-requisite: CHEM 360. Three credits and laboratory.
- March 2006 -

462 Topics in Analysis and Spectroscopy
Topics are typically selected from the following: NMR, Fluorescence, FTIR, Raman, Methods used for Surface Analysis, Capillary electrophoresis, Mass Spectrometry, Flow Injection Analysis and Process Analytical Chemistry. Lab experiments will be carried out to complement the course work.
Pre- or co-requisite: CHEM 360. Three credits and laboratory.
- March 2006 -

491 Chemistry Seminar II (Outline)
Presentations by visitors, faculty, staff, senior honours and advanced major students on aspects of chemical science. Attendance is mandatory for students in all B.Sc. and M.Sc. degree programs where chemistry is Science A. No formal credit is given for this course, but satisfactory completion of senior essays from majors students, senior essays and presentations from advanced majors students, and presentations based on their theses from honours students, are requirements for the B.Sc. degree.
NOTE: the above course requirement for majors students begins in 2008/09.
- February 2007 -

493 Honours Thesis (eg Outline)
Based upon a program of experimental research involving the use of modern chemical techniques to solve a problem in the areas of analytical, inorganic, organic, or physical chemistry. An acceptable thesis based on the research must be submitted before the conclusion of lectures for the academic year to satisfy the department requirements for the B.Sc. with Honours in chemistry.
Three credits and laboratory.
- June 2004 -